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BOOK Vitamin B12 deficiency in clinical practice - B12d Patient Case Studies

In the course of Dr Chandy's work, we observed thousands of patients and a number of them consented to have their case studies compiled into the book in 2019 (www.b12d.org/book) and prior to that (2014) into a compentium, which is enclosed here.

B12 deficiency case studies from 2014

page Details
9

Energy/ Haemopoetic system 

Extreme fatigue, ME/CFS, fibromyalgia, often combined with endocrine system malfunction (also see endocrine on pg 29)
10 Mother and daughter: B12 deficiency without macrocytosis but with neuropsychiatric symptoms
11 B12 deficiency and hypoadrenalism
12 Child withdrawn and lacking energy
13

Neurological case studies

Numbness, pins & needles, phantom pains, loss of power, SACD
14

Single limb paralysis
15

Mother champions the cause for her daughters
16

Left oculomotor nerve paralysis
17

Lhermitte's Sign
18

Motor nerve damage
19

Facial weakness/ palsy
20

MS-like presentation
21

Bell's Palsy affecting left side of face
22

Ramsay-Hunt syndrome
23

Psychiatric Symptoms
24

Totally drained, depressed, skin rash all over his body
25

ME, Depression, Fibromyalgia, Munchausen's by proxy, joint pain
26

Eye, Ear, Throat

Glossopharyngeal nerve pathology leading to difficulty swallowing, persistent cough, etc
27

Glossopharyngiditis
28

Persistent cough and swallowing difficulty, lasting 1 year
29

Immune system and Autoimmune conditions case studies

B12 not only affects the red blood cells, it also affects platelets and white cells, including immune system
30

Can people die of B12 deficiency? Two case studies contrasted
31

B12 and Adrenal insufficiency
32

Common immunodeficiency
33

Cardiovascular/ respiratory system 

Palpitations, chest pain, heart-disease-like presentation, breathlessness and asthma-like presentation
34

Cardiomyopathy and mitral-aortic defect in pregnant mother
35

Vasculitis due to B12 deficiency/ hypoadrenalism
36

Erupto-xanthoma
37

Gastro-intestinal tract

Colitis, IBS, Mouth Ulcers
38

Swallowing difficulty, extremely incoherent speech and colitis
39

Skin, hair, connective tissue, joints
40

Subtle cobalamin deficiency with clinically deficient presentation ME, fibromyalgia, myositis
42

Rheumatoid arthritis
43

Alopecia
44

Lupus, Rheumatoid arthritis & Raynaud's Disease
45

Ankylosing spondylitis/ sacroiliitis
46

Genito-urinary system

Incontinence, infertility, miscarriage
47

Fertility and tiredness
48

Familiy inheritance of B12 deficiency, B12 deficiency in children

including problems of folic acid supplementation without B12 in pregnancy
49

Four generations
50

Genetic incidence is clear
51

Mother and children

B12 deficiency case studies from 2014

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B12d Charity Support Group Blog

  • 08
    MAR

    NICE Guidelines for B12d published 6 March 2024 - Guidelines and our response

    After months (some would say years) of careful lobbying...

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  • 17
    MAY

    Case studies from 2014 uploaded

    Way back before we thought of publishing a book, we cre...

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  • 04
    MAY

    May 2020 Newsletter

    The newsletter is available as a PDF, with an article a...

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  • 23
    MAR

    Coronavirus and meetings moved online

    Vitamin B12 is vital for the immune system.  This ...

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Donna, like so many women, wants to live a normal life. Vitamin B12 could give her that chance.
The local MP (Grahame Morris MP for Easington - who was a BMS (BioMedical Scientist) in the labs at Sunderland Royal Infirmary) interviews people with B12 deficiency to hear their story (August 27 2010). Here Jane describes the symptoms, and how she can't wait for her next B12 injection (in fact, she knows that she needs injections every 2 weeks because she's keeping a diary of the symptoms). We're restricted how often the GP can give injections, which is why we want to raise awareness.
June describes her suffering when doctors didn't follow the standard protocol after any stomach or intestinal operation - to offer B12 replacement therapy
The definitive and original guide to B12 deficiency, Dr Chandy interviewed by Chris Jackson of UK BBC Inside Out Team broadcast 31 Oct 2008.
Dr Joseph Chandy explains symptoms and shows the restorative effect on one patient (other patients' families have asked that we edit out their stories unfortunately)
Frankie tells of how she suffered, the tests she had to endure until doctors worked out what was wrong, and what a difference it has made.
Dr Chandy was nominated for the North East Local Heroes award. The interviewer was at first surprised - people don't get awards for doing what they are paid to do - but she persisted.
Janette first appeared in the BBC InsideOut documentary in October 2006. Since then the NHS has forced her doctor to withdraw B12 replacement therapy on a number of occasions, and she tells of her struggles with having B12 and then having it taken away.
She has bravely agreed to be filmed without her usual wig, but her memory is playing up because it is so long since her last injection.
Julia found her eyesight going as her eyes refused to focus on the same things as each other. She's been for all sorts of tests and treatment, but now that she's on B12 replacement therapy she's starting to see an improvement.
Susan gets very tired, which isn't much fun especially as she has so much to do. Here she tells her story.
Just the way it works for humans, oral B12 can make a world of a difference for your pet. My old cat Smudge chases the young cat again, climbs ladders (and climbs down herself), and is generally as fit as she was many years ago.